Table 1.
Cell type | Gene markers | LIHC | |||||
---|---|---|---|---|---|---|---|
None | Purity | Age | |||||
COR | P | COR | P | COR | P | ||
B cells | CD79A | 0.156 | 2.54E-03 | 0.289 | 4.46E-08 | 0.139 | 7.67E-03 |
CD19 | 0.269 | 1.36E-07 | 0.361 | 4.57E-12 | 0.251 | 1.18E-06 | |
CD86 | 0.271 | 1.17E-07 | 0.438 | 1.29E-17 | 0.271 | 1.47E-07 | |
CD8+ T cells | CD8A | 0.194 | 1.38E-04 | 0.323 | 7.60E-10 | 0.196 | 1.58E-04 |
CD8B | 0.201 | 9.72E-05 | 0.32 | 1.14E-09 | 0.203 | 9.51E-05 | |
Neutrophils | CCR7 | 0.073 | 1.62E-01 | 0.23 | 1.61E-05 | 0.058 | 2.71E-01 |
SIGLEC5 | 0.226 | 1.09E-05 | 0.366 | 2.23E-12 | 0.224 | 1.55E-05 | |
KIR2DL3 | 0.187 | 2.84E-04 | 0.238 | 7.85E-06 | 0.194 | 1.84E-04 | |
KIR2DL4 | 0.23 | 7.56E-06 | 0.271 | 3.09E-07 | 0.25 | 1.24E-06 | |
CSF3R | 0.254 | 6.79E-07 | 0.403 | 6.93E-15 | 0.247 | 1.76E-06 | |
FPR1 | 0.183 | 3.99E-04 | 0.33 | 3.26E-10 | 0.187 | 3.22E-04 | |
Dendritic cells | CD209 | 0.093 | 7.38E-02 | 0.181 | 7.16E-04 | 0.1 | 5.67E-02 |
ITGAX | 0.283 | 2.85E-08 | 0.425 | 1.37E-16 | 0.282 | 3.86E-08 | |
STAT4 | 0.242 | 2.24E-06 | 0.314 | 2.42E-09 | 0.23 | 9.15E-06 | |
STAT1 | 0.335 | 3.76E-11 | 0.387 | 8.70E-14 | 0.33 | 9.45E-11 | |
Monocyte | CSF1R | 0.142 | 6.23E-03 | 0.3 | 1.25E-08 | 0.146 | 5.24E-03 |
CCL2 | 0.07 | 1.81E-01 | 0.195 | 2.74E-04 | 0.062 | 2.34E-01 | |
CD68 | 0.204 | 7.48E-05 | 0.309 | 4.66E-09 | 0.206 | 7.33E-05 | |
Treg cells | FOXP3 | 0.147 | 4.57E-03 | 0.233 | 1.25E-05 | 0.172 | 9.75E-04 |
PD1 | 0.315 | 5.63E-10 | 0.428 | 9.06E-17 | 0.304 | 2.92E-09 | |
CCR8 | 0.319 | 3.23E-10 | 0.422 | 2.66E-16 | 0.322 | 3.02E-10 | |
Macrophages | PTGS2 | 0.056 | 2.84E-01 | 0.189 | 4.02E-04 | 0.038 | 4.66E-01 |
CD163 | 0.039 | 4.51E-01 | 0.16 | 2.93E-03 | 0.045 | 3.93E-01 | |
MS4A4A | 0.057 | 2.72E-01 | 0.2 | 1.79E-04 | 0.06 | 2.52E-01 | |
CEACAM8 | 0.054 | 2.97E-01 | 0.088 | 1.01E-01 | 0.049 | 3.53E-01 | |
Natural killer cells | KIR3DL3 | 0.045 | 3.84E-01 | 0.053 | 3.23E-01 | 0.038 | 4.72E-01 |
KIR2DS4 | 0.078 | 1.33E-01 | 0.077 | 1.51E-01 | 0.072 | 1.67E-01 |
COR, r value of Spearman’s correlation; Purity, correlation adjusted by purity; Age, correlation adjusted by age.