Table 2.
Cumulative incidence of cause-specific mortality at landmark ages
| Age at diagnosis | AF diagnosis, < 1990, N = 683 | AF diagnosis, 1990-2002, N = 711 | AF diagnosis, ≥ 2003, N = 731 | Ptrend value |
|---|---|---|---|---|
| < 70 years (cumulative incidence at age 75 years) | ||||
| CVD death | 67.7 (40.8, 91.3) | 17.9 (10.2, 30.4) | 13.9 (6.9, 26.8) | < 0.001 |
| Non-CVD death | 18.2 (6.9, 42.9) | 41.8 (29.5, 56.7) | 32.9 (20.6, 50.0) | 0.07 |
| Unknown death | 0.6 (0.2, 2.1) | 3.2 (1.3, 8.0) | 3.2 (0.9, 11.1) | 0.74 |
| Between 70 and < 80 years (cumulative incidence at age 85 years) | ||||
| CVD death | 58.9 (48.0, 70.2) | 27.4 (18.8, 39.1) | 18.9 (9.0, 37.5) | < 0.001 |
| Non-CVD death | 26.5 (18.7, 36.9) | 44.5 (34.4, 55.9) | 47.8 (27.0, 73.8) | 0.30 |
| Unknown death | 4.4 (2.2, 8.6) | 4.7 (2.3, 9.2) | 5.2 (2.5, 10.8) | 0.86 |
| ≥ 80 years (cumulative incidence at age 95 years) | ||||
| CVD death | 32.9 (14.4, 63.9) | 56.9 (42.8, 71.9) | 26.7 (14.9, 45.0) | 0.76 |
| Non-CVD death | 62.1 (36.2, 87.7) | 34.3 (23.3, 48.4) | 62.5 (44.5, 80.5) | 0.002 |
| Unknown death | 4.5 (1.7, 11.5) | 6.4 (3.5, 11.4) | 7.5 (3.5, 15.7) | 0.83 |
In each group according to age at AF diagnosis, we tested for linear trends over epochs of AF diagnosis in the cumulative incidence function for cause-specific death