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. 2021 Jul 12;6(29):19252–19268. doi: 10.1021/acsomega.1c02665

Table 8. IC50 Values of All Compounds on DL, EAC, and PBMC Cell Linesa.

  IC50 (μM)
cells cisplatin 3 7 8 9 10 11
DL cells 0.19 ± 0.07 112 ± 3.4 93 ± 2.8 8.3 ± 0.05 1.7 ± 0.06 15.8 ± 0.05 63.7 ± 1.3
SI PBMC/DL 79.15 1.33 4.28 19.42 82.88 9.18 6.72
EAC cells 0.37 ± 0.10 122.8 ± 2.8 103.8 ± 0.82 18.2 ± 0.05 13.7 ± 0.03 21.4 ± 0.57 87.3 ± 1.6
SI PBMC/EAC 40.64 1.22 3.83 8.86 10.28 6.78 4.90
PBMCs 15.04 ± 0.05 149.9 ± 1.2 397.6 ± 3.5 161.2 ± 2.8 140.9 ± 1.5 145.1 ± 1.8 428.1 ± 3.1
a

Dose–response curves were used for the calculation of IC50. SI refers to the selectivity index computed by IC50 (PBMC)/IC50 (DL or EAC).