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. 2021 Jul 12;6(29):18890–18903. doi: 10.1021/acsomega.1c02118

Table 3. cSAR(X) Ranges of Variation for Studied Solvents, Presented as the Mean Values for Two Tautomers Characterized by Similar Proximity; ε from 1.0 (Gas Phase) up to ε = 108.94 (Formamide).

X position of substitution Tautomers type of proximity mean range of cSAR(X) values ratio (I-type/II-type)
NO2 C8 9H, 7H II-type 0.054 2.35
    3H, 1H I-type 0.127  
  C2 9H, 7H I-type 0.080 3.08
    3H, 1H II-type 0.026  
H C8 9H, 7H II-type 0.024 1.42
    3H, 1H I-type 0.034  
  C2 9H, 7H I-type 0.032 0.89
    3H, 1H II-type 0.036  
NH2 C8 9H, 7H II-type 0.062 0.48
    3H, 1H I-type 0.030  
  C2 9H, 7H I-type 0.007 0.09
    3H, 1H II-type 0.078