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CSF CHIT1 levels in nusinersen-naïve SMA patients
| All SMA patients (n = 79) | Adult SMA patients (n = 58) | Pediatric SMA patients (n = 21) | Controls (n = 30) | |
|---|---|---|---|---|
| CSF CHIT1 (pg/mL), median (IQR) | 1787 (959–2866) | 1838 (1035–3133) | 1294 (883–2657) | 563 (563–971) |
| Range | 563–9810 | 563–9810 | 563–8341 | 563–3058 |
| Below LLOQ, n (%) | 12 (15) | 8 (14) | 4 (19) | 17 (57) |
CHIT1 Chitotriosidase 1 concentration, CSF cerebrospinal fluid, IQR interquartile range, LLOQ lower limit of quantification (< 563 pg/mL)
