Table 2.
Immunohistochemistry results of the CMA
| Cell line | Primary site | AUC | p53 wt DNA | p53 mutation | Immunohistochemistry | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| p53 | LIMA1 | EGFR | NDFIP1 | Oct4 | CIP2A | |||||
| UT-SCC-2 | floor of mouth | 1.8 ± 0.2 | no | c.275 CCC > CAT | mutated | 1 | 3 | 0 | 1 | 2 |
| UT-SCC-5 | tongue | 2.3 ± 0.3 | no | c.151 CCC > CAT | mutated | 2 | 3 | 1 | 1 | 1 |
| UT-SCC-7 | temporal skin | 2.0 ± 0.2 | yes | c.266 GGA > GAA | mutated | 1 | 3 | 1 | 1 | 3 |
| UT-SCC-8 | supraglottic | 1.9 ± 0.1 | no | c.255 ATC > TTC | mutated | 1 | 3 | 1 | 1 | 2 |
| UT-SCC-9 | glottic | 1.4 ± 0.1 | no | total deletion | absent | 1 | 2 | 0 | 0 | 2 |
| UT-SCC-14 | tongue | 1.7 ± 0.3 | yes | deletion, frameshift | mutated | 1 | 3 | 0 | 1 | 2 |
| UT-SCC-16A | tongue | 1.8 ± 0.1 | c.110 CGT > TGT / c.232 ATC > AAC | mutated | 1 | 2 | 0 | 0 | 1 | |
| UT-SCC-17 | supraglottic | 1.8. ± 0.1 | c.110 CGT > CTT / c.257 CTG > CAG | mutated | 2 | 3 | 1 | 1 | 3 | |
| UT-SCC-19A | glottic | 1.7 ± 0.1 | no | c.285 GAG>AAG | mutated | 2 | 3 | 0 | 0 | 3 |
| UT-SCC-20A | floor of mouth | 2.1 ± 0.2 | yes | c.248 CGG > TGG | mutated | 2 | 2 | 1 | 1 | 2 |
| UT-SCC-24A | tongue | 2.6 ± 0.3 | yes | 47 bp insertion, frameshift | absent | 2 | 3 | 1 | 1 | 3 |
| UT-SCC-25 | tongue | no | c.248 CGG > TGG | mutated | 2 | 3 | 1 | 1 | 2 | |
| UT-SCC-30 | tongue | 2.0 ± 0.1 | no | c.282 CGG > CCG | mutated | 1 | 2 | 0 | 1 | 1 |
| UT-SCC-32 | tongue | 1.7 ± 0.3 | no | c.266 GGA > GAA | mutated | 1 | 3 | 1 | 0 | 1 |
| UT-SCC-34 | supraglottic | 2.0 ± 0.1 | yes | total deletion | absent | 1 | 3 | 1 | 1 | 1 |
| UT-SCC-36 | floor of mouth | 2.2 ± 0.2 | no | c.244 GGC > AGC | mutated | 1 | 2 | 1 | 1 | 3 |
| UT-SCC-45 | floor of mouth | 2.0 ± 0.1 | wt | 1 | 3 | 0 | 1 | 1 | ||
| UT-SCC-46A | retromolar gingiva | 1.6 ± 0.1 | wt | 1 | 1 | 0 | 0 | 1 | ||
| UT-SCC-47 | floor of mouth | 2.0 ± 0.2 | absent | 2 | 2 | 1 | 1 | 3 | ||
| UT-SCC-50 | glottic | wt | 2 | 3 | 1 | 1 | 2 | |||
| UT-SCC-60B | tonsil | 2.2 ± 0.3 | absent | 2 | 2 | 0 | 1 | 2 | ||
| UT-SCC-72 | mandibular gingiva | 2.8 ± 0.2 | absent | 2 | 3 | 1 | 1 | 2 | ||
| UT-SCC-74A | tongue | wt | 1 | 3 | 0 | 1 | 2 | |||
| UT-SCC-76A | tongue | 2.5 ± 0.2 | mutated | 1 | 3 | 0 | 0 | 1 | ||
| UT-SCC-79A | parotid | 2.4 ± 0.2 | yes | deletion, frameshift | wt | 2 | 3 | 1 | 1 | 1 |
| UT-SCC-79B | parotid | 2.5 ± 0.1 | yes | deletion, frameshift | wt | 2 | 2 | 1 | 1 | 1 |