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. 2021 Jul 28;26:81. doi: 10.1186/s40001-021-00555-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Resveratrol reduces the production of Interlukin-6 and inhibits the activation of JAK/STAT3 pathway. A Relative mRNA level of IL-6 and STAT3 both decreased in a dose-dependent manner (*p < 0.05). B Western blot of key proteins in IL-6/JAK/STAT3 pathway. The results showed that the protein level of IL-6, P-JAK1, P-STAT3 decreased more obviously than the other and decreased in a dose-dependent manner. C Quantified analysis (grey value analysis) of western blot results (*p < 0.05)