Table 2.

Summary of ethical amendments

Protocol	Date	Summary of changes
V3	24.05.2018	Funding and approval secured to expand the study to allow multicentre recruitment and NIHR portfolio adoption
V4.1	15.10.2018	Additional exclusion criteria added: Mirena coil in situ or removed within the last 3 months. Any other condition that would compromise participant safety or data integrity.
V4.3	06.03.2020	Approval to allow recruitment strategy to include proven endometrial cancer cases prior to hysterectomy
V4.4	16.07.2020	Approval to allow remote consent and data collection, if required, as part of COVID-19 safety mitigation measures

NIHR, National Institute for Health Research.