Table 1.
Baseline characteristics of patients visiting the neuropsychiatric systemic lupus erythematosus (NPSLE) clinic between 2007 and 2015
| All patients (n=151) |
Minor/non-NPSLE (n=115) | Inflammatory NPSLE (n=24) | Ischaemic NPSLE (n=12) | |
| Female | 138 (92) | 106 (92) | 22 (92) | 10 (83) |
| Age | 41.9±13.3 | 42.3±13.0 | 39.5±15.5 | 42.2±11.5 |
| Duration of SLE, years | 5 (0–30) | 7 (0–30) | 1 (0–21) | 7 (1–29) |
| SLEDAI-2K | 4 (0–34) | 4 (0–18) | 8 (0–34) | 4.5 (0–8) |
| SDI | 1 (0–5) | 0 (0–5] | 1 (0–4) | 1 (0–4) |
| BMI | 24.6±4.5 | 24.6±4.4 | 24.1±5.2 | 25.9±4.7 |
| Current smoking | 49 (32) | 39 (34) | 6 (25) | 4 (33) |
| Education | ||||
| Low | 7 (5) | 4 (4) | 1 (4) | 2 (17) |
| Middle | 90 (60) | 70 (61) | 12 (50) | 8 (67) |
| High | 54 (36) | 41 (36) | 11 (46) | 2 (17) |
| Comorbidities | ||||
| Hypertension | 53 (35) | 38 (33) | 10 (42) | 5 (42) |
| Diabetes | 4 (3) | 4 (4) | 0 (0) | 0 (0) |
| Antiphospholipid syndrome | 19 (13) | 13 (11) | 3 (13) | 3 (25) |
| Brain volumes (in mL) | ||||
| White matter volume | 481±56 | 485±51 | 473±53 | 483±57 |
| Grey matter volume | 561±60 | 564±44 | 562±63 | 561±61 |
| Total brain volume | 1045±108 | 1046±111 | 1028±94 | 1050±107 |
| WMH volume | 0.7 (0–48) | 0.6 (0–48) | 1.1 (0–30] | 1.1 (0–10) |
Data represent n (%), mean±SD or median (range).
BMI, body mass index; SDI, SLICC/ACR Damage Index; SLE, systemic lupus erythematosus; SLEDAI-2K, Systemic Lupus Erythematosus Disease Activity Index 2000; WMH, white matter hyperintensity.