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. 2021 Jun 28;8(7):ofab344. doi: 10.1093/ofid/ofab344

Figure 4.

Figure 4.

(A) Composition of serum samples tested and sorted by diagnosis category. (B) Calculated EIA units in all patient serum tested, separated by diagnostic category. Blue inverted triangles represent patients with proven diagnosis, while orange squares indicate patients with proven coccidioidomycosis whose disease appeared to be resolved at time of specimen collection (no symptoms and negative serology, see Supplementary Table 2). A dotted line represents the cutoff value for positivity at 32.5 units, with any value above this categorized as a negative result (shaded area). (C) Correlation of EIA units with serologic antibody titers determined by complement fixation. Individual dots on the left side of the line show EIA units determined by ELISA in 51 proven and probable patients with a positive CF titer (grouped by CF titer on x-axis). Individual dots on the right side of the line show EIA units in 27 proven and probable patients with a negative CF titer and either positive or negative ID results. Average EIA units by titer are represented with a horizontal black line.