Table 7:

Description of the activities performed by the severely impaired patients in the cohort (2/2).

Activity	Workspace	Target object(s)	Instructions*
			Proximal >Distal	Proximal <Distal
Drinking	Tabletop with water bottle and paper cup 18 cm to the left and right of midline, 25 cm from edge closest to patient	Water bottle (12 oz), paper cup	Reach to touch object on paretic side. Reach across to touch object on non-paretic side.	Starting from upright position, lay object on paretic side horizontally, release, and return to upright. Perform same series of actions on the object on the non-paretic side.
Tooth brushing	Sink with toothpaste and toothbrush on either side of the countertop, 30 cm from edge closest to patient	Travel-sized toothpaste on left, toothbrush with built-up foam grip on right, faucet handle	Reach to touch object on paretic side. Place toothbrush in paretic hand and bring it to mouth.	Lift object on paretic side for 3 seconds.
Moving object on a horizontal surface	Horizontal circular array (48.5 cm diameter) of 8 targets (5 cm diameter)	Toilet paper roll (200 g) or can (200 g)	Investigator will assess if toilet paper roll can be grasped, or aluminum can if not. If grasp is possible, move roll/can between the center and each outer target, resting before and after each motion. If grasp is not possible, the toilet paper roll will be moved around the target array by the investigator and the patient will reach to touch it at each location.	Investigator will assess if toilet paper roll can be grasped, or aluminum can if not. If grasp is not possible, the toilet paper roll will be moved around the target array by the investigator and the patient will reach to touch it at each location.
Moving object on/off a Shelf	Shelf with two levels (33 cm and 53 cm) with 3 targets on both levels (22.5 cm, 45 cm, and 67.5 cm away from the left-most edge)	Toilet paper roll (200 g) or can (200 g)	Investigator will assess if toilet paper roll can be grasped, or aluminum can if not. If grasp is possible, move roll/can between the center and each outer target, resting before and after each motion. If grasp is not possible, the toilet paper roll will be moved around the target array by the investigator and the patient will reach to touch it at each location.	Investigator will assess if toilet paper roll can be grasped, or aluminum can if not. If grasp is not possible, the toilet paper roll will be moved around the target array by the investigator and the patient will reach to touch it at each location.