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. 2021 Jul 15;12:711359. doi: 10.3389/fmicb.2021.711359

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Copyright © 2021 Nogal, Louca, Zhang, Wells, Steves, Spector, Falchi, Valdes and Menni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of the flowchart (A) integrating gut microbiota composition and diversity, visceral fat and circulating acetate levels, and (B) showing the applied filters and conducted steps to genomically characterize the Lachnoclostridium spp. and Coprococcus spp. Steps exclusively applied for Lachnoclostridium and Coprococcus are indicated in orange and green, respectively, whereas the rest of steps were conducted in the genomes from both species. ANI, average nucleotide identity; LMM, linear mixed model; UHGG, Unified Human Gastrointestinal Genome; QC, quality control.