Plasma total (▼), 14,15- (●), 11,12- (●), and 8,9 (○)-epoxyeicosatrienoic acid (EET, A) and dihydroxyeicosatrienoic acid (DHET, B) concentrations before (Pre) and three to twelve months after (Post) treatment of primary aldosteronism. Soluble epoxide hydrolase (sEH) activity was estimated indirectly by the molar ratios of individual and total DHET/(EET+DHET) (C). Data for individual EET concentrations appear in Figure S1.