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. 2021 Jul 15;9:614324. doi: 10.3389/fbioe.2021.614324

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Copyright © 2021 Grzesik and Warth.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of optimal number of clusters by the “elbow” method using the total within Sum of Squares (upper panel). Evaluation of cluster integrity by calculation of Silhouette width of each cluster (lower panel).