Table 2.
Sleep disorders among 572 hospitalized patients with COVID-19: prevalence and unadjusted association with mechanical ventilation, vasopressor requirement, death, and length of stay.
Sleep Diagnosis | All* (n = 572) | Mechanical Ventilation* (n = 109) | OR [95% CI] | Vasopressor Requirement* (n = 102) | OR [95% CI] | Death* (n = 72) | OR [95% CI] | LOS† (n = 572) | HR to Discharge [95% CI] |
---|---|---|---|---|---|---|---|---|---|
OSA | 113 (19.8) | 28 (25.7) | 1.54 [0.94, 2.51] | 26 (25.5) | 1.51 [0.91, 2.49] | 16 (22.2) | 1.19 [0.65, 2.16] | 8 (3, 43) | 0.92 [0.74, 1.15] |
Insomnia | 63 (11.0) | 14 (12.8) | 1.25 [0.66, 2.35] | 16 (15.7) | 1.67 [0.91, 3.01] | 12 (16.7) | 1.76 [0.89, 3.49] | 12 (4, 76) | 0.81 [0.61, 1.08] |
RLS/PLMD | 22 (3.9) | 1 (0.9) | 0.20 [0.02, 1.47] | 2 (2.0) | 0.45 [0.10, 1.96] | 3 (4.2) | 1.10 [0.32, 3.82] | 10.5 (5, 42) | 0.86 [0.54, 1.35] |
Values are n (%). †Values are median (interquartile range). CI = confidence interval, HR = hazard ratio, LOS = length of stay, OR = odds ratio, OSA = obstructive sleep apnea, PLMD = periodic limb movement disorder, RLS = restless legs syndrome.