Table 3.
Results of mediation analyses.
| Potential mediators | Intervention Effect on Change in Potential Mediators* (A) | Association between Change in Potential Mediators and Change in GSDS Scores* (B) | Indirect Effect (AB), β Coefficient (95% CI) | ||
|---|---|---|---|---|---|
| β Coefficient (95% CI) | P | β Coefficient (95% CI) | P | ||
| PSS | 2.07 (0.37, 3.76) | .02 | 0.35 (−0.05, 0.74) | .09 | 0.72 (−0.19, 2.06) |
| BDI-II | 4.22 (1.31, 7.12) | .005 | 0.61 (0.38, 0.84) | < .001 | 2.58 (0.69, 5.09) |
| TNF | 0.22 (−0.11, 0.55) | .18 | 0.92 (−1.04, 2.88) | .36 | 0.21 (−0.32, 0.79) |
| IL-6 | 0.22 (0.01, 0.44) | .04 | −2.10 (−5.15, 0.95) | .18 | −0.47 (−1.51, 0.34) |
Total effect (C): β Coefficient = 4.91; 95% CI = 0.24, 9.57; P = .04. Direct effect (C′): β Coefficient = 1.87; 95% CI = −2.55, 6.29; P = .40. Overall indirect effect: β Coefficient = 3.03; 95% CI = 0.59, 5.79. *Denotes the change from T0 to T2, such that positive numbers indicate decrease in sleep disturbance/stress/depressive symptoms/TNF/IL-6 levels from T0 to T2 (ie, improvement). BDI-II = Beck Depression Inventory, version II; CI = confidence interval; GSDS = General Sleep Disturbance Scale; IL-6 = interleukin 6; PSS = Perceived Stress Scale; TNF = tumor necrosis factor.