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. 2021 Jul 15;11:714159. doi: 10.3389/fonc.2021.714159

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Copyright © 2021 Yu, Zhang, Zhou, Shen, Xing and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Difference in RNA expression between CCL244 and HCT116 after irradiation. (A) LncRNAs differentially expressed in CCL244 and HCT116 after 8 Gy radiation exposure. (log2(foldchange)>=1 or log2(foldchange)<=-1, and p value<=0.05 were considered a statistically significant difference). (B) CCL244 and HCT116 co-exist differentially expressed lncRNAs. (C) Six miRNAs with differences were detected. (D) Starbase database predicted the interaction of lnc-TLCD2-1 with miRNA (Score>=0.8). (E) The expression of lnc-TLCD2-1 was significantly changed after radiation. (F) MiR-193a-5p was significantly changed after radiation. (P<=0.05 means statistically significant, **p < 0.01, ****p < 0.0001.)