Table 1.
Number of differentially expressed genes for each dose and length of exposure compared to time-matched control groups (shown as total DEG (Up-regulated [↑], Down-regulated [↓])). Full DESeq2 results can be found in Supplemental Table S1.
| Exposure Duration (days) | 1,4-Dioxane Concentration (ppm) |
||||
|---|---|---|---|---|---|
| 40 | 200 | 600 | 2000 | 6000 | |
| 7 | 0 (0) | 2 (↑0, ↓2) | 411 (↑165, ↓246) | 20 (↑6, ↓14) | 415 (↑180, ↓235) |
| 28 | 1 (↑0, ↓1) | 1 (↑0, ↓1) | 1 (↑0, ↓1) | 49 (↑21, ↓28) | 232 (↑87, ↓145) |
| 90 | 5 (↑1, ↓4) | 22 (↑11, ↓11) | 323 (↑165, ↓158) | 33 (↑25, ↓8) | 727 (↑352, ↓375) |