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Pleuromutilin-22-mesylate – predicted EC3 values for different assumptions regarding reactivity and RAI coefficient EC3 value in bold results from the calculation presented in the text.
| Estimated EC3 for k(CH2CO2R)/kCH2R = | |||
|---|---|---|---|
| RAI coefficient | 1000 | 1400 | 2000 |
| 1.5 | 0.004% | 0.002% | 0.001% |
| 1 | 0.06% | 0.04% | 0.03% |
| 0.5 | 1.1% | 0.9% | 0.7% |
