Fig. 3.

Transcript expression of Tshr (A), Nis (B), Pds (D), Tpo (E) and Mct-8 (F) in thyroid and serum T4 (G) and T3 (H) concentrations of rats exposed to 0 (control), 2.5 or 5 mg/kg acrylamide of BW. The ribosomal protein L19 (Rpl19) mRNA content was used as an internal control. Correlation between Nis and Tshr mRNA contents (C) (Pearson correlation coefficient r = 0.75; P < 0.001). Values are expressed as the means ± SEM (ANOVA followed by the post-test of Dunnett), *P < 0.05 and **P < 0.01 vs. control, # 0.05 < P ≤ 0.1. Tshr: thyroid stimulating hormone receptor; Nis: sodium/iodide symporter; Pds: pendrin; Tpo: thyroid peroxidase; Mct-8: monocarboxylate transporter 8; T3: triiodothyronine; T4: thyroxine; BW: body weight.