TABLE 3.
Amplitude (pA) | Rise time (ms) | Area (pA × ms) | Decay time (ms) | |
---|---|---|---|---|
sEPSCs | ||||
WT 2 month | 6.4 ± 0.4 | 1.0 ± 0.08 | 35.5 ± 4.8 | 4.3 ± 0.5 |
Q175 2 month | 6.7 ± 5.0 | 1.0 ± 0.15 | 27.2 ± 5.3 | 4.7 ± 0.5 |
WT 12 month | 6.5 ± 0.4 | 1.1 ± 0.09 | 47.2 ± 10.1 | 4.3 ± 0.9 |
Q175 12 month | 6.9 ± 0.5 | 1.1 ± 0.08 | 42.6 ± 9.7 | 4.5 ± 0.5 |
sIPSCs | ||||
WT 2 month | 13.3 ± 0.6 | 3.0 ± 0.24 | 470.1 ± 40.2 | 18.5 ± 1.5 |
Q175 2 month | 13.5 ± 0.4 | 2.7 ± 0.24 | 459.1 ± 12.2 | 15.7 ± 1.1 |
WT 12 month | 13.4 ± 0.4 | 3.0 ± 0.13 | 487.2 ± 22.4 | 18.2 ± 0.8 |
Q175 12 month | 13.6 ± 0.7 | 3.0 ± 0.09 | 484.9 ± 44.6 | 16.9 ± 1.2 |