Table 2.
Univariate Cox regression and multivariate Cox regression analysis of riskScore and clinical information in TCGA and MSKCC cohorts.
| Variables | Unicox | Multicox | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI of HR | P | HR | 95%CI of HR | P | |
| TCGA | ||||||
| age | 1.00 | 0.99-1.06 | 0.192 | |||
| Gleason(10/9/8/7/6) | 2.20 | 1.76-2.83 | <0.001 | 2.00 | 1.52-2.57 | <0.001 |
| T(T4/T3/T2) | 2.60 | 1.66-3.95 | <0.001 | 1.08 | 1.04-1.13 | <0.001 |
| N(N1/N0) | 1.70 | 1.03-2.85 | 0.037 | 0.80 | 0.46-1.39 | 0.425 |
| PSA | 1.10 | 1.03-1.10 | <0.001 | 1.00 | 0.99-1.07 | 0.101 |
| riskScore | 1.11 | 1.07-1.15 | <0.001 | 1.89 | 1.01-3.52 | 0.044 |
| MSKCC | ||||||
| age | 1.02 | 0.97-1.08 | 0.381 | |||
| Gleason(10/9/8/7/6) | 3.7 | 2.57-5.33 | <0.001 | 3.28 | 2.22-4.86 | <0.001 |
| T(T3/T2/T1) | 1.53 | 0.74-3.15 | 0.257 | |||
| riskScore | 1.76 | 1.43-2.17 | <0.001 | 1.39 | 1.07-1.79 | 0.016 |