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. 2021 Jul 15;12:690647. doi: 10.3389/fmicb.2021.690647

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Copyright © 2021 Elangovan, Jenks, Yun, Dickson-Tetteh, Kirtley, Hemelaar and WHO-UNAIDS Network for HIV Isolation and Characterisation.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Global distribution of HIV-1 variants before and after reassignment of CRFs to “pure” HIV-1 subtypes. (A) Global proportions of HIV-1 subtypes A–K, CRF01_AE, CRF02_AG, other CRFs and URFs, based on most recent data available for each country. (B–E) Global proportions of HIV-1 variants after reassignment of CRFs to “pure” HIV-1 subtypes, based on full-length sequence (B), gag (C), pol (D), and env (E). CRF, circulating recombinant form; URF, unique recombinant form. Data underlying this figure is displayed in Supplementary Material, pp. 8–10.