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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Magn Reson Med. 2020 Mar 11;84(4):2147–2160. doi: 10.1002/mrm.28237

TABLE 5.

Comparison of FRAPPE vessel wall measurements between high and low atherosclerosis risk groups

Variable Risk Group
Difference
High (N = 50) Low (N = 50) Mean (95% CI) P-value AUC (95% CI)
Mean wall thickness, mm 0.82 ± 0.08 0.76 ± 0.06 0.06 (0.02, 0.10) 0.004 0.71 (0.57, 0.84)
Max wall thickness, mm 1.97 ± 0.56 1.57 ± 0.43 0.40 (0.16, 0.63) 0.002 0.73 (0.60, 0.85)
Mean eccentricity ratio 1.47 ± 0.20 1.34 ± 0.15 0.13 (0.04, 0.22) 0.005 0.79 (0.68, 0.89)
Mean wall area, mm2 17 ± 4 16 ± 4 1.2 (−0.9, 3.3) 0.25 0.60 (0.44, 0.75)
Mean lumen area, mm2 27 ± 8 28 ± 11 −1.0 (−6.3, 4.2) 0.72 0.50 (0.34, 0.67)
Mean total vessel area, mm2 45 ± 12 44 ± 15 0.2 (−7.1, 7.3) 0.95 0.53 (0.37, 0.69)
Mean normalized wall index, % 39 ± 3 38 ± 4 1.7 (−0.2, 3.5) 0.073 0.65 (0.49, 0.79)
Max normalized wall index, % 49 ± 6 46 ± 7 2.9 (−0.5, 6.2) 0.091 0.64 (0.49, 0.77)

Abbreviations: AUC, area under the receiver operating characteristic curve; CI, confidence interval; FRAPPE, fully automated and robust analysis technique for popliteal artery evaluation.