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. 2021 Jul 15;9:655819. doi: 10.3389/fcell.2021.655819

TABLE 1.

The genes associated with the pathogenesis of PD.

Gene Full name Locus Location
SNCA Synuclein alpha PARK1 4q22.1 Azizi and Azizi (2018)
Parkin Parkin RBR E3 ubiquitin protein ligase PARK2 6q26 Morato Torres et al. (2020)
PARK3 Parkinson disease 3 PARK3 2p13 Kachidian and Gubellini (2021)
SNCA Synuclein alpha PARK4 4q22 Forero et al. (2020)
UCHL1 Ubiquitin C-terminal hydrolase L1 PARK5 4p13 Kachidian and Gubellini (2021)
PINK1 PTEN induced putative kinase 1 PARK6 1p36 Li D. et al. (2020)
PARK7 Parkinsonism associated deglycase PARK7 1p36.23 Li Y. et al. (2020)
LRRK2 Leucine rich repeat kinase 2 PARK8 12q12 Li D. et al. (2020)
ATPase 13A2 ATPase 13A2 PARK9 1p36.13 Gago et al. (2020)
PARK10 Parkinson disease 10 PARK10 1p32 Kachidian and Gubellini (2021)
GIGYF2 GRB10 interacting GYF protein PARK11 2q37.1 Calatayud et al. (2017)
PARK12 Parkinson disease 12 PARK12 Xq21-q25 Zanon (2020)
HTRA2 HtrA serine peptidase 2 PARK13 2p13.1 Zanon (2020)
PLA2G6 Phospholipase A2 group VI PARK14 22q13.1 Sudira et al. (2018)
FBXO7 F-box protein 7 PARK15 22q12.3 Yuan et al. (2017)
PARK16 Parkinson disease 16 PARK16 1q32 Han et al. (2019)
VPS35 VPS35, retromer complex component PARK17 16q11.2 Cutillo et al. (2020)
EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 PARK18 3q27.1 Li D. et al. (2020)
DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 PARK19 1p31.3 Velez-Pardo and Jimenez-Del-Rio (2020)
SYNJ1 Synaptojanin 1 PARK20 21q22.1 Zanon (2020)
TMEM230 Transmembrane protein 230 PARK21 20p13 Deng et al. (2018)
CHCHD2 Coiled-coil-helix-coiled-coil-helix domain containing 2 PARK22 7p11.2 Velez-Pardo and Jimenez-Del-Rio (2020)
VPS13C RIC3 Vacuolar protein sorting 13 homolog C acetylcholine receptor chaperone RIC3 PARK23 15q22.2 11p15.4 Zanon (2020)