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. 2021 Jul 29;16(7):e0255194. doi: 10.1371/journal.pone.0255194

Table 3. Univariable and multivariable models for odds of TB vs. non-TB patients by host characteristics, in the elderly or adults.

Elderly: TB vs non-TB Adults: TB vs non-TB
OR (95% CI) Model 1 a: Model 2 b: OR (95% CI) Model 1: Model 2:
Adj-OR (95% CI) Adj-OR (95% CI)
Adj-OR (95% CI) Exclude BMI, glycemia Adj-OR (95% CI) Exclude BMI, glycemia
Male vs female sex 6.93 (3.23, 14.87) 3.92 (1.41, 10.88) 4.33 (1.76, 10.65) 2.65 (1.61, 4.37) 2.80 (1.49, 5.25) 2.63 (1.56, 4.46)
Smoking, ’Past’ vs ’current or never’ 5.37 (2.46, 11.70) 5.43 (1.627, 18.122) 2.55 (1.008, 6.449) 4.71 (2.68, 8.29) 5.41 (2.57, 11.38) 3.99 (2.21, 7.19)
BCG vaccine, No vs Yes 7.86 (3.13, 19.74) 5.36 (1.68, 17.10) 6.15 (2.24, 16.92) 1.17 (0.56, 2.44) 0.73 (0.30, 1.77) 0.98 (0.45, 2.16)
Glycemia            
    Normoglycemia 1.0 1.0   1.0 1.0  
    Impaired Fasting Glucose 0.22 (0.05, 0.99) 0.38 (0.06, 2.38)   2.11 (0.93, 4.76) 5.84 (2.07, 16.49)  
    Hyperglycemia 0.54 (0.24, 1.25) 0.52 (0.18, 1.46)   3.30 (1.92, 5.80) 4.37 (2.22, 8.58)  
Diabetes 1.07 (0.54, 2.12)     2.88 (1.71, 4.84)    
Obesity            
    Underweight/normal 12.99 (5.34, 31.58) 12.34 (4.44, 34.33)   9.01 (5.26, 15.42) 14.30 (7.48, 27.32)  
    Overweight/Obese 1.0 1.0   1.0 1.0  

a Model-1. Controlled for all variables in the table.

b Model-2. Model 1, except for BMI and glycemia; 95% CI with p values ≤ 0.099 shown in bold; In sensitivity analysis, additional models were evaluated: Model 1A. When glycemia was replaced by diabetes (2 categories) in Model 1, diabetes remained associated with TB in adults (adj-OR 4.08, 95% CI 2.13, 7.80), but not in the elderly [adj-OR 1.70 (0.65, 4.45)]. Model 1B. Addition of education or health insurance did not modify the associations already observed in Model 1.