Table 3. Univariable and multivariable models for odds of TB vs. non-TB patients by host characteristics, in the elderly or adults.
Elderly: TB vs non-TB | Adults: TB vs non-TB | |||||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | Model 1 a: | Model 2 b: | OR (95% CI) | Model 1: | Model 2: | |||
Adj-OR (95% CI) | Adj-OR (95% CI) | |||||||
Adj-OR (95% CI) | Exclude BMI, glycemia | Adj-OR (95% CI) | Exclude BMI, glycemia | |||||
Male vs female sex | 6.93 (3.23, 14.87) | 3.92 (1.41, 10.88) | 4.33 (1.76, 10.65) | 2.65 (1.61, 4.37) | 2.80 (1.49, 5.25) | 2.63 (1.56, 4.46) | ||
Smoking, ’Past’ vs ’current or never’ | 5.37 (2.46, 11.70) | 5.43 (1.627, 18.122) | 2.55 (1.008, 6.449) | 4.71 (2.68, 8.29) | 5.41 (2.57, 11.38) | 3.99 (2.21, 7.19) | ||
BCG vaccine, No vs Yes | 7.86 (3.13, 19.74) | 5.36 (1.68, 17.10) | 6.15 (2.24, 16.92) | 1.17 (0.56, 2.44) | 0.73 (0.30, 1.77) | 0.98 (0.45, 2.16) | ||
Glycemia | ||||||||
Normoglycemia | 1.0 | 1.0 | 1.0 | 1.0 | ||||
Impaired Fasting Glucose | 0.22 (0.05, 0.99) | 0.38 (0.06, 2.38) | 2.11 (0.93, 4.76) | 5.84 (2.07, 16.49) | ||||
Hyperglycemia | 0.54 (0.24, 1.25) | 0.52 (0.18, 1.46) | 3.30 (1.92, 5.80) | 4.37 (2.22, 8.58) | ||||
Diabetes | 1.07 (0.54, 2.12) | 2.88 (1.71, 4.84) | ||||||
Obesity | ||||||||
Underweight/normal | 12.99 (5.34, 31.58) | 12.34 (4.44, 34.33) | 9.01 (5.26, 15.42) | 14.30 (7.48, 27.32) | ||||
Overweight/Obese | 1.0 | 1.0 | 1.0 | 1.0 |
a Model-1. Controlled for all variables in the table.
b Model-2. Model 1, except for BMI and glycemia; 95% CI with p values ≤ 0.099 shown in bold; In sensitivity analysis, additional models were evaluated: Model 1A. When glycemia was replaced by diabetes (2 categories) in Model 1, diabetes remained associated with TB in adults (adj-OR 4.08, 95% CI 2.13, 7.80), but not in the elderly [adj-OR 1.70 (0.65, 4.45)]. Model 1B. Addition of education or health insurance did not modify the associations already observed in Model 1.