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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Stroke. 2021 May 5;52(6):2162–2173. doi: 10.1161/STROKEAHA.120.032736

Fig. 4. CARD9 activation (ACT) CRISPR abolished the beneficial effects of LP17 at 24h after ICH.

Fig. 4

(A) Modified Garcia test and limb placement test at 24h after ICH. (B) Representative immunoblot bands and (C) Quantitative analysis of TREM-1, PLC-γ, PKC δ, CARD9, NF-κB p65, IL-1β, TNF-α, TGF-β and Arg-1 expressions in the ipsilateral hemisphere at 24h after ICH. The error bars represent mean±SD. *P<0.05 vs sham, #P<0.05 vs ICH, @P<0.05 vs LP17. N=6 per group.