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(A) unsupervised NMF and (B) t-SNE analyses of the RNA-Seq gene-expression table. The 52 patients with MB were classified into WNT (7), SHH (17), Group 3 (14), and Group 4 (14). Abbreviations: NMF: Nonnegative matrix factorization; t-SNE: t-distributed stochastic neighbor embedding; WNT: Wingless; SHH: Sonic hedgehog; MB: Medulloblastoma.
