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. 2021 Jul 29;16(7):e0255500. doi: 10.1371/journal.pone.0255500

Table 1. Clinical profiles of the study cohort.

WNT SHH Group 3 Group 4
Case number 7 12 8 11
Age at diagnosis 6.2 ± 4.1 5.5 ± 4.5 8.3 ± 5.1 10.0 ± 2.9
Boy–girl ratio 1:6 5:7 5:3 6:5
Clinical risk stratification
Non-met (M0-1) AR 7 7 4 3
Non-met (M0-1) HR 0 3 3 5
Met (M2-3) HR 0 2 1 3
Treatment strategy
CMT alone 0 1 0 0
RT alone 0 1 1 1
RT + CMT 7 9 7 10

Abbreviations: WNT: Wingless; SHH: Sonic hedgehog; Met: Metastasis; AR: Average risk; HR: High risk; CMT: Chemotherapy; RT: Radiation therapy.