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. 2021 Jul 29;16(7):e0254958. doi: 10.1371/journal.pone.0254958

Table 2. Demographics by epoch and surgical approach.

Pre-pandemic Pandemic p-value
Dates 3/1/2019–1/31/2020 3/1/2020–1/31/2021 NA
Patients (n = 295) 163 132 NA
Total Operations (n = 317) 172 (54%) 145 (46%) NA
Mean Age (±SD) 53.2±15.8 52.3±17.6 0.63
Female 95 (58.3%) 69 (52.3%) 0.35
Prior Surgery 39 (23.9%) 34 (25.8%) 0.79
Emergent Surgery 11 (6.4%) 9 (6.2%) 1.0
Craniotomy Cohort
Patients (n = 163) 82 81 NA
Total Operations (n = 179) 91 88 NA
Mean Age (±SD) 57.2±14.9 55.2±17.6 0.43
Prior Surgery 21 (25%) 23 (28%)
ASA 0.28
1 4 (4%) 1 (1%)
2 22 (25%) 21 (24%)
3 61 (67%) 57 (65%)
4 4 (4%) 9 (10%)
Pathology
Meningioma 33 (36%) 20 (23%)
Glioma 31 (34%) 32 (36%)
Metastatic Tumor 15 (17%) 20 (23%)
Schwannoma 3 (3%) 4 (4%)
Other* 9 (10%) 12 (14%)
Endonasal Cohort
Patients (n = 132) 79 53 NA
Total Operations (n = 138) 81 57 NA
Mean Age (±SD) 49.1±15.7 48.1±16.9 0.73
Prior Surgery 18 (23%) 11 (21%) 0.83
ASA 0.70
1 1 (1%) 1 (2%)
2 37 (46%) 22 (39%)
3 43 (53%) 34 (59%)
Pathology
Pituitary Adenoma 52 (64%) 39 (68%)
Meningioma 7 (9%) 4 (7%)
Craniopharyngioma 7 (9%) 1 (2%)
Rathke’s Cleft Cyst 5 (6%) 8 (14%)
Chordoma 3 (3%) 1 (2%)
Other* 7 (9%) 4 (7%)

For Craniotomy, other includes: arachnoid cyst, chordoma, pituitary adenoma, pineal parenchymal tumor, germinoma, neuroblastoma, RCC, dermoid cyst, epidermoid cyst, colloid cyst, sinonasal and neuroendocrine carcinoma, hemangioblastoma, hemangiopericytoma. For Endonasal other includes: sinonasal carcinoma, germinoma, glioma, epidermoid cyst, chondrosarcoma, granular cell tumor, ameloblastoma.