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. 2021 Jul 19;17(7):e1009668. doi: 10.1371/journal.ppat.1009668

Fig 5. SARS-CoV-2-specific CD8+ T-cell responses.

Fig 5

(A) Representative gating schema for detection of IFN-γ induction after stimulation with overlapping M&E peptide pools in macaque N012 on day 14 post-infection. (B) Frequencies of CD8+ T cells targeting S, N, and M&E in PBMCs on days 7, 14, and 21 post-infection in Group N animals infected with 106 (middle) or 105 (right) TCID50 of SARS-CoV-2. (C) Frequencies of CD8+ T cells targeting S, N, and M & E in submandibular lymph nodes obtained at necropsy in macaques N011, N013, N021, and N022. Samples were unavailable for analysis in macaque N012.