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. 2021 Jul 29;398(10300):599–607. doi: 10.1016/S0140-6736(21)00896-5

Table 3.

IRR of ischaemic stroke following COVID-19 in the SCCS

Number of events IRR (95% CI) p value
Ischaemic stroke analysis 1 (day 0 out of the risk period)
Control period 123 1 (ref) ..
Buffer period: days −28 to −4 57 1·95 (1·25–3·04) 0·0031
Pre-exposure period: days −3 to 0 33 11·28 (7·15–17·80) <0·0001
Risk period: days 1 to 7 16 2·97 (1·71–5·15) 0·0001
Risk period: days 8 to 14 14 2·80 (1·60–4·88) 0·0003
Risk period: days 15 to 28 11 2·10 (1·33–3·32) 0·0015
Ischaemic stroke analysis 2 (day 0 in the risk period)
Control period 123 1 (ref) ..
Buffer period: days −28 to −4 57 1·89 (1·21–2·96) 0·0048
Pre-exposure period: days −3 to −1 8 3·96 (1·85–8·45) 0·0004
Risk period: days 0 to 7 41 6·18 (4·06–9·42) <0·0001
Risk period: days 8 to 14 14 2·85 (1·64–4·97) 0·0002
Risk period: days 15 to 28 11 2·14 (1·36–3·38) 0·0011

IRR=incidence rate ratio. SCCS=self-controlled case series.