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. 2021 Jul 15;11:704039. doi: 10.3389/fonc.2021.704039

Table 1.

Related studies and methodology of CT-/MRI-based bladder image segmentation during the past 20 years.

Study Imaging Approach or strategy Region focused Performance and Merits
Li et al., 2004 (86) Multispectral MRI Partial volume (PV) scheme IB More information extracted from the multispectral images, and feasible for the IB.
Li et al., 2008 (85) Multispectral MRI Markov random field (MRF) IB Realizing the inhomogeneity correction and overcoming the influence of partial volume and bias field.
Duan et al., 2010 (80) T1WI Coupled level-sets *IB/OB Realizing the simultaneous extraction of both IB and OB of the bladder.
Garnier et al., 2011 (87) T2WI 3D deformable model based on active region growing strategy IB/OB Achieving good performance for the IB segmentation when tumors were not existed in the bladder lumen.
Duan et al., 2011 (78) T1WI Coupled level-sets + volume-based features Tumor Realizing the automatic detection of BCa.
Duan et al., 2012 (79) T1WI Coupled level-sets + volume-based features + Adaptive window-setting scheme Tumor Realizing the automatic detection and extraction of BCa.
Ma et al., 2011 (88) T2WI Geodesic active contour (GAC) + shape-guided Chan-Vese IB/OB Achieving good segmentation performance for both bladder borders without tumor regions using two datasets with 2D images.
Han et al., 2013 (89) T1WI Adaptive MRF with coupled level-set constraints IB/OB Fast convergence, robustness to initial estimates, and robustness against noise contaminations, as well as local shape variations of the bladder wall.
Qin et al., 2014 (77) T2WI Coupled directional level-sets with adaptive shape prior constraints IB/OB With the average DSC of 0.96 and 0.946, respectively, for the IB and OB segmentation using 11 datasets.
Cha et al., 2014 (90) #CECT Conjoint level set analysis and segmentation system (CLASS) IB/OB With the average DSC of 0.842 for the IB segmentation using 182 datasets.
Dolz et al., 2018 (83) T2WI Progressive dilated convolution-based U-NET model IB/OB/Tumor With the average DSC of 0.9836, 0.8391 and 0.6856, respectively, for the IB, OB and tumor region segmentation using 60 datasets.
Gordon et al., 2018 (91) CECT Deep-learning convolutional neural network (DL-CNN) IB/OB With the average DSC of 0.9869 and 0.875, respectively, for the IB and OB segmentation using 172 datasets.
Ma et al., 2019 (92) CECT U-Net–based deep learning approach (U-DL) IB With the average DSC of 0.934 for the IB segmentation using 173 datasets.

*IB and OB represent the inner and outer borders of bladder, respectively.

#CECT indicates contrast-enhanced CT.