Table 1.
Main Candidate Genes with Divergent Alleles Derived from Standing Genetic Variation.
| HDR | NCBI Name | Allelic Origina |
|---|---|---|
| chilotes specific | Cytochrome P450 2K1 [XP_014266774.1] | Before LT |
| sauvagei specific | Signal transducer and activator of transcription 1-alpha/beta [XP_003441521.1] | Before HB |
| Phospholipid phosphatase-related protein type 4 [XP_005456534.1] | Before HB | |
| rufus specific | Cadherin-related family member 5-like [XP_005454335.1] | Before HB |
| Collagen alpha-6(VI) chain [XP_019219949.1] | Before HB | |
| Fibrinogen alpha chain [XP_013119750.1] | Before HB | |
| Fibrinogen beta chain [XP_003455581.2] | Before HB | |
| General transcription factor IIF subunit 2 [XP_005466907.1] | Before LT | |
| chilotes-sauvagei | Cathepsin L1 [XP_003453258.1] | Before LT |
| Transient receptor potential cation channel subfamily M member 4 [XP_019218187.1] | Before HB | |
| chilotes-rufus | Collagen alpha-6(VI) chain [XP_019219953.1] | Before LT |
| Intestinal mucin-like protein [XP_024659051.1] | Before LT | |
| Membrane cofactor protein [XP_025757175.1] | Before HB | |
| sauvagei-rufus | Toll-like receptor 2 [XP_013119752.1] | Before LM |
| TRPM8 channel-associated factor homolog [XP_014268336.2] | Before HB | |
| TRPM8 channel-associated factor homolog [XP_024660658.1] | Before HB |
a
Allelic origin indicates when the gene acquired divergent allele. LT, LM, and HB are the abbreviations of Lake Tanganyika, Lake Malawi, and Haplochromis burtoni from rivers near Lake Tanganyika, respectively.