Table 1. Plasmodium falciparum lines employed herein.
Parasite | Origin | Year | K13 | Resistance |
---|---|---|---|---|
3D7WT | Africa | 1981 | WT | -- |
F32WT | Tanzania | 1982 | WT | -- |
UG659WT | Uganda | 2007 | WT | CQ, SP |
UG815WT | Uganda | 2008 | WT | CQ, SP |
Dd2WT | Indochina | 1980 | WT | CQ, MFQ, SP |
Cam3.IIWT | Cambodia | 2010 | WT | CQ, SP |
CamWTC580Y | Cambodia | 2010 | C580Y | ART, CQ, SP |
RF7C580Y | Cambodia | 2012 | C580Y | ART, CQ, PPQ, SP |
Thai1WT | Thailand | 2003 | WT | CQ, SP |
Thai2WT | Thailand | 2004 | WT | CQ, MFQ, SP |
Thai3WT | Thailand | 2003 | WT | CQ, SP |
Thai4WT | Thailand | 2003 | WT | CQ, SP |
Thai5WT | Thailand | 2011 | WT | CQ, SP |
Thai6E252Q | Thailand | 2008 | E252Q | ART (low), CQ, MFQ, SP |
Thai7E252Q | Thailand | 2010 | E252Q | ART (low), CQ, MFQ, SP |
Parasite superscripts refer to the K13 sequence.
ART, artemisinin; CQ, chloroquine; MFQ, mefloquine; PPQ, piperaquine; SP, sulfadoxine/pyrimethamine; WT, wild type.