Table 3.

Various applicable strategies for enhancing the patient's comfort during PICC insertion based on their age. Derived in accordance with Westergaard et al. [43] and Vineet et al. [64].

Age group	Sedation strategy
Younger than 6–8 years	For this age group, it is recommended to use general anesthesia to achieve the most appropriate outcomes which gives more comfort to the patients during PICC placement.
6–8 years	Due to the fact that the patients within this group are older and more capable of tolerating the possible complications of PICC placement, the application of nitrous oxide, local anesthesia, and premedication is enough and there is no need for general anesthesia.
Older than 6–8 years	Administering premedication for achieving local anesthesia is considered to be an effective method within this age group.