Table 3.
SNP | Genotype | NEC group n (%) | Control group n (%) | Statistics | P value |
---|---|---|---|---|---|
A385T | AA | 9 (26.47) | 12 (33.33) | χ 2 = 4.154 | P=0.125● |
AT | 12 (35.29) | 17 (47.22) | |||
TT | 13 (38.24) | 7 (19.44) | |||
AA + AT | 21 (61.76) | 29 (80.56) | χ 2 = 3.025 | P=0.082Δ | |
A allele | 30 (44.12) | 42 (58.33) | χ 2 = 2.829 | P=0.065☆ | |
T allele | 38 (55.88) | 30 (41.67) | |||
| |||||
C357T | CC | 0 (0) | 0 (0) | ||
CT | 7 (20.59) | 4 (10.26) | |||
TT | 27 (79.41) | 32 (89.74) | χ 2 = 1.186 | P=0.276 | |
C allele | 7 (10.29) | 4 (5.56) | |||
T allele | 61 (89.71) | 68 (94.44) | χ 2 = 1.085 | P=0.234 | |
G428A | GG | 68 (100) | 72 (100) |
Note. ● comparing the three genotypes of the A385T locus in the NEC group and the control group, there is a certain difference in the genetic polymorphism composition of the two groups, but P > 0.05, with no statistical significance; Δ comparing the number of TT genotypes at the locus of A385T of the two groups, it was found that the NEC group had more homozygous mutant TT types than the control group, but P > 0.05, which was not statistically significant; ☆ comparing the number of A allele and T allele at the A385T locus of the two groups, P > 0.05, which was not statistically significant.