Table 1.

Animal characteristics

	Young		Old
Characteristics	Vehicle	Apigenin	Vehicle	Apigenin
n	10	10	7	9
Body weight, g	31.1 ± 1.5	30.6 ± 1.1	30.9 ± 1.3	29.7 ± 1.1
Energy intake, kcals/day	15.3 ± 0.3	15.8 ± 0.2	15.3 ± 0.9	14.4 ± 0.6
Water intake, mL/day	4.3 ± 0.1	4.0 ± 0.1	5.4 ± 1.5*	5.1 ± 1.8*
Apigenin intake, mg/day		2.0 ± 0.1		2.5 ± 0.9
Heart mass, mg	146.0 ± 5.9	133.7 ± 4.8	163.3 ± 12.1*	166.0 ± 7.8*
Quadriceps mass, mg	312.5 ± 12.1	336.9 ± 16.1	240.0 ± 10.1*	251.7 ± 15.5*
Visceral adipose mass, g	1.1 ± 0.2	1.0 ± 0.1	0.3 ± 0.1*	0.2 ± 0.1*
Carotid artery
Resting diameter, µM	361 ± 5	357 ± 6	370 ± 8	386 ± 10
Maximal diameter, µM	402 ± 6	410 ± 9	437 ± 11*	440 ± 8*
Aorta
Diameter, µM	613 ± 8	635 ± 19	636 ± 8	646 ± 21
Intima media thickness, µM	39 ± 1	36 ± 2	60 ± 4*	54 ± 4*
Systolic blood pressure, mm/Hg
Pre	106 ± 2	101 ± 3	96 ± 6	98 ± 6
Post	100 ± 4	97 ± 3	98 ± 4	96 ± 3
Diastolic blood pressure, mm/Hg
Pre	79 ± 4	75 ± 4	77 ± 3	75 ± 6
Post	75 ± 2	78 ± 3	76 ± 4	74 ± 5

Values are means ± SE; n, number of mice.

*P < 0.05 young vehicle vs. old vehicle; young apigenin vs. old apigenin.