Table 3.

Male body weight, tissue masses (in grams), and postabsorptive blood plasma lipids in wild-type and myoglobin knockout mice following ∼13 wk of feeding a high-fat diet (45% of energy)

	WT	Mb−/−	t Test P Valuea
Body weight	33.8 ± 1.26	34.8 ± 1.45	0.63
Brain	0.462 ± 0.011	0.473 ± 0.011	0.47
Liver	1.230 ± 0.041	1.330 ± 0.078	0.29
Cecumb	0.187 ± 0.018	0.195 ± 0.013	0.74
Adiposec
Total adipose	4.116 ± 0.284	3.900 ± 0.201	0.54
Subcutaneous	1.083 ± 0.091	1.062 ± 0.082	0.87
Inguinal	0.258 ± 0.023	0.245 ± 0.014	0.65
Perigonadal	1.917 ± 0.134	1.742 ± 0.094	0.30
Retroperitoneal	0.545 ± 0.039	0.514 ± 0.022	0.50
Brown adipose tissue	0.314 ± 0.020	0.337 ± 0.028	0.50
Muscled
Heart	0.139 ± 0.003	0.149 ± 0.005	0.08
Left gastrocnemius	0.124 ± 0.003	0.130 ± 0.003	0.23
Left plantaris	0.018 ± 0.0005	0.017 ± 0.0007	0.35
Left soleus	0.009 ± 0.001	0.009 ± 0.0004	0.76
Left extensor digitorum longus	0.009 ± 0.0005	0.009 ± 0.0005	0.42
Plasma Lipids
Triglycerides (mg/dL)	23.4 ± 1.1	23.1 ± 0.5	0.86
Nonesterified fatty acids (μM)	332 ± 8	341 ± 19	0.65

^aTwo-tailed t test; n = 10/genotype.

^bCecum was not emptied.

^cMasses of left and right fat pads; “total adipose” is the summed weight of all measured white adipose pads.

^dMass of the left-side muscle only. Mb^−/−,myoglobin knockout; WT, wild-type.