TABLE 1.

Decide whether the quality of evidence and identified undesirable effects¹ support making a quantified dietary bioactive intake recommendation based on systematic evidence reviews

Quality of evidence grade	Decision to make a quantified recommendation
Moderate or higher	Yes, contingent on 2 criteria being met:1) demonstrated efficacy occurs at levels considered safe, and 2) bioactive benefits outweigh potential undesirable1 effects
Less than moderate	No

¹Undesirable effects identified by the expert panel other than “safety” can include whether intake of energy, nutrients, or recommended food groups are likely to change in an undesirable direction.