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. 2021 Jun 25;297(2):100889. doi: 10.1016/j.jbc.2021.100889

Table 1.

APOBEC3 mutational activities by sequencing analyses of HBV 1360-2090 nt PCR

Treatment Total sequenced clones (n) Mutation-positive clones (x/n) Total C-to-T # detected Average C-to-T# per clone Mutation efficiency (% of 180 cytidinesa) Mutation efficiency average (%)
Vector 40 1/40 7 7 3.9 3.9
A3B 40 4/40 247 61.8 3.9–55 34.3
A3C 40 20/40 162 8.1 1.7–11.7 4.5
A3G 40 8/40 102 12.8 1.7–17.2 7.1
A3H-II 40 4/40 55 13.8 2.8–12.8 7.7

The # stands for C-to-T mutation number.

a

There are 180 cytidines available to potential mutation in the HBV 1360 to 2090 nt.