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. 2021 Jul 15;7(7):e07581. doi: 10.1016/j.heliyon.2021.e07581

Table 2.

The calculated stability constants and the achieved solubility enhancement based on phase solubility study.

Cyclodextrin K (mean ± SD, n = 3) Maximum solubility enhancement (CD concentration)
α- 2.7 ± 0.5 1.10 × (30mM)
β- 97.2 ± 3.1 2.16 × (11.8 mM)
γ- 30.3 ± 0.8 1.70 × (30 mM)
HP-β- DS 3 68.5 ± 1.1 3.27 × (30 mM)
HP-β- DS 4.5 129.9 ± 2.2 4.66 × (30 mM)
HP-β- DS 6 87.7 ± 2.8 3.69 × (30 mM)
RAMEB 101.7 ± 1.7 3.75 × (30mM)
TRIMEB 24.0 ± 0.6 1.74 × (30mM)
SBE-β-CD DS 7 194.6 ± 1.0 6.93 × (30mM)