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. 2021 Jul 17;23:100284. doi: 10.1016/j.pacs.2021.100284

Fig. 8.

Fig. 8

In vivo PA test results of the stabilities of GNSs with and without silica shells. (a) US and PA fused images of a mouse tumor containing bare GNSs, showing the decreasing of the PA signal intensities from the GNSs during laser irradiation. (b) US and PA fused images of a mouse tumor containing silica-coated GNSs, demonstrating improved stability during laser irradiation. (c) Average PA pixel intensities in the ROI in the tumors as a function of time during laser irradiation. The measurement from bare GNSs (black circles) is compared to that from the silica-coated GNSs (red squares). (d) Attenuation of PA signal intensities from bare GNSs and silica-coated GNSs measured in tumors in vivo during laser irradiation (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article).