Fig. 2. Effect of filtering thresholds on mutation-rate estimation.

The mutation rate and spectrum of the gray mouse lemur, as a product of two main filtering decisions: (1) an allelic balance filter (along the rows) and (2) a callable site filter (along the columns). The first three columns display how the parent-of-origin, the mutation rate at CpG sites, and total number of mutations vary. The remainder of the table shows the combined effect of these filters on the calculated rate. Cells for lower rates are shaded blue and higher rates are shaded red. All mutation rates have been corrected for the estimated number of false positives and false negatives with their respective number of mutations and callable sites.