Table 1.

Approved dosing regimen

Product	Recommended dosing regimen
Adalimumab	80 mg starting dose, followed after 1 week by 40 mg every 2 weeks. Beyond 16 weeks, patients with inadequate response to 40 mg every 2 weeks may benefit from an increase in dosage to 40 mg every week or 80 mg every 2 weeks
Etanercept	25 mg twice weekly OR 50 mg once weekly OR 50 mg twice weekly for 12 weeks followed by 25 mg twice weekly OR 50 mg once weekly for up to 24 weeks. Treatment should be discontinued in patients who show no response after 12 weeks
Infliximab	5 mg/kg starting dose, then 5 mg/kg after 2 weeks, followed by 5 mg/kg after 4 weeks, then 5 mg/kg every 8 weeks. Treatment should be discontinued in patients who show no response after 14 weeks
Secukinumab	300 mg once weekly for 5 weeks, then maintenance 300 mg every month. Each 300 mg dose is given as two injections of 150 mg
Ustekinumab	For bodyweight < 100 kg: Initially 45 mg, then 45 mg after 4 weeks, then 45 mg every 12 weeks For bodyweight ≥ 100 kg: Initially 90 mg, then 90 mg after 4 weeks, then 90 mg every 12 weeks