Table 2.
Results of univariable analysis for cancer recurrence or death among patients.
| Total (n = 3010) | Recur | p value | Death | p value | ||||
|---|---|---|---|---|---|---|---|---|
| Yes (n = 657) | Yes (n = 1229) | |||||||
| N | % | N | % | N | % | |||
| Gender | ||||||||
| Female | 146 | 4.9 | 34 | 23.3 | 0.661 | 60 | 41.1 | 0.947 |
| Male | 2864 | 95.1 | 623 | 21.8 | 1169 | 40.8 | ||
| Age | ||||||||
| ≤ 40 | 201 | 6.7 | 48 | 23.9 | 0.044 | 68 | 33.8 | < 0.001 |
| 41–50 | 677 | 22.5 | 175 | 25.8 | 279 | 41.2 | ||
| 51–60 | 1067 | 35.4 | 218 | 20.4 | 413 | 38.7 | ||
| 61–70 | 684 | 22.7 | 136 | 19.9 | 264 | 38.6 | ||
| ≥ 71 | 381 | 12.7 | 80 | 21.0 | 205 | 53.8 | ||
| Smoking | ||||||||
| No | 589 | 19.6 | 145 | 24.6 | 0.068 | 246 | 41.8 | 0.607 |
| Yes | 2421 | 80.4 | 512 | 21.1 | 983 | 40.6 | ||
| Betel nut | ||||||||
| No | 970 | 32.2 | 229 | 23.6 | 0.103 | 403 | 41.5 | 0.582 |
| Yes | 2040 | 67.8 | 428 | 21.0 | 826 | 40.5 | ||
| Alcohol | ||||||||
| No | 1014 | 33.7 | 239 | 23.6 | 0.099 | 407 | 40.1 | 0.582 |
| Yes | 1996 | 66.3 | 418 | 20.9 | 822 | 41.2 | ||
| T stage | ||||||||
| 1 | 1320 | 43.9 | 243 | 18.4 | < 0.001 | 404 | 30.6 | < 0.001 |
| 2 | 722 | 24.0 | 168 | 23.3 | 299 | 41.4 | ||
| 3 | 173 | 5.7 | 40 | 23.1 | 83 | 48.0 | ||
| 4 | 795 | 26.4 | 206 | 25.9 | 443 | 55.7 | ||
| N stage | ||||||||
| Without ND | 664 | 22.1 | 164 | 24.7 | < 0.001 | 277 | 41.7 | < 0.001 |
| 0 | 1700 | 56.5 | 276 | 16.2 | 566 | 33.3 | ||
| 1 | 223 | 7.4 | 63 | 28.3 | 114 | 51.1 | ||
| 2 | 394 | 13.1 | 142 | 36.0 | 258 | 65.5 | ||
| 3 | 29 | 1.0 | 12 | 41.4 | 14 | 48.3 | ||
| Stage | ||||||||
| Early | 1766 | 58.7 | 328 | 18.6 | < 0.001 | 573 | 32.4 | < 0.001 |
| Advance | 1244 | 41.3 | 329 | 26.4 | 656 | 52.7 | ||
| ECS | ||||||||
| Without ND | 664 | 22.1 | 164 | 24.7 | < 0.001 | 277 | 41.7 | < 0.001 |
| No | 2113 | 70.2 | 404 | 19.1 | 801 | 37.9 | ||
| Yes | 233 | 7.7 | 89 | 38.2 | 151 | 64.8 | ||
| Neck LV IV and V metastasis | ||||||||
| No | 2937 | 97.6 | 632 | 21.5 | 0.009 | 1182 | 40.2 | < 0.001 |
| Yes | 73 | 2.4 | 25 | 34.2 | 47 | 64.4 | ||
| Contralateral neck metastasis | ||||||||
| No | 3004 | 99.8 | 655 | 21.8 | 0.495 | 1227 | 40.8 | 0.708 |
| Skip metastasis | ||||||||
| Yes | 6 | 0.2 | 2 | 33.3 | 2 | 33.3 | ||
| No | 2957 | 98.2 | 639 | 21.6 | 0.031 | 1203 | 40.7 | 0.219 |
| Yes | 53 | 1.8 | 18 | 34.0 | 26 | 49.1 | ||
| Close margin | ||||||||
| No | 2898 | 96.3 | 636 | 21.9 | 0.422 | 1180 | 40.7 | 0.522 |
| Yes | 112 | 3.7 | 21 | 18.8 | 49 | 43.8 | ||
| Grade | ||||||||
| Well | 514 | 17.5 | 76 | 14.8 | < 0.001 | 136 | 26.5 | < 0.001 |
| Moderately | 2269 | 77.5 | 512 | 22.6 | 968 | 42.7 | ||
| Poorly | 146 | 5.0 | 47 | 32.2 | 86 | 58.9 | ||
| Anatomic site | ||||||||
| Buccal mucosa | 1050 | 34.9 | 221 | 21.0 | 0.044 | 368 | 35.0 | < 0.001 |
| Alveolar ridge | 482 | 16.0 | 108 | 22.4 | 233 | 48.3 | ||
| Ant tongue | 884 | 29.4 | 208 | 23.5 | 371 | 42.0 | ||
| Hard palate | 87 | 2.9 | 18 | 20.7 | 53 | 60.9 | ||
| Floor of mouth | 85 | 2.8 | 16 | 18.8 | 33 | 38.8 | ||
| RMT | 158 | 5.2 | 46 | 29.1 | 76 | 48.1 | ||
| Mucosal lip | 73 | 2.4 | 10 | 13.7 | 21 | 28.8 | ||
| Body of the lip | 191 | 6.3 | 30 | 15.7 | 74 | 38.7 | ||
| Recur | ||||||||
| No | 2353 | 78.2 | 734 | 31.2 | < 0.001 | |||
| Yes | 657 | 21.8 | 495 | 75.3 | ||||
| Dead | ||||||||
| No | 1781 | 59.2 | 162 | 9.1 | < 0.001 | |||
| Yes | 1229 | 40.8 | 495 | 40.3 | ||||