Table 3.

Multiple Cox proportional hazards regression analysis of disease-free survival.

Cox proportional-hazards regression analysis of disease free survival
	Total	Recur or death		Univariate analysis (crude)			Multiple analysis (adjusted)
		N	%	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
Age
≤ 40	201	82	40.8	1.000			1.000
41–50	677	316	46.7	1.228	0.963–1.566	0.097	1.315	1.029–1.680	0.029
51–60	1067	470	44.0	1.167	0.923–1.476	0.196	1.256	0.990–1.594	0.060
61–70	684	306	44.7	1.239	0.971–1.582	0.085	1.426	1.113–1.829	0.005
≥ 71	381	217	57.0	1.712	1.327–2.208	< 0.001	2.042	1.574–2.648	< 0.001
Anatomic subsite
Buccal mucosa	1050	441	42.0	1.000			1.000
Alveolar ridge	482	252	52.3	1.384	1.186–1.616	< 0.001	1.220	1.036–1.436	0.017
Ant tongue	884	413	46.7	1.164	1.018–1.331	0.027	1.133	0.990–1.297	0.069
Hard palate	87	55	63.2	1.877	1.418–2.485	< 0.001	1.848	1.394–2.450	< 0.001
Floor of mouth	85	38	44.7	1.174	0.843–1.636	0.343	1.185	0.850–1.652	0.317
RMT	158	85	53.8	1.331	1.055–1.679	0.016	1.190	0.941–1.504	0.147
Mucosal lip	73	24	32.9	0.834	0.553–1.258	0.386	0.918	0.608–1.386	0.683
Body of the lip	191	83	43.5	0.942	0.745–1.191	0.616	1.031	0.814–1.307	0.799
T stage
1	1320	497	37.7	1.000			1.000
2	722	342	47.4	1.395	1.215–1.601	< 0.001	1.271	1.105–1.462	0.001
3	173	88	50.9	1.715	1.367–2.152	< 0.001	1.487	1.181–1.871	0.001
4	795	464	58.4	1.904	1.678–2.161	< 0.001	1.585	1.379–1.823	< 0.001
N positive
No	2364	992	42.0	1.000			1.000
Yes	646	399	61.8	1.959	1.744–2.201	< 0.001	1.828	1.615–2.070	< 0.001

Follow-up time: from OSCC diagnosed to recur, death, or 2019–12-31.

RMT retromolar trigone.