Figure 2.

Volcano plots representing the log₂ fold change against the corresponding – log₁₀ p_adj-value of all genes for each of the three brain regions studied: (a) hypothalamus, (b) BnSt, (c) Tn. Differentially expressed genes (p_adj < 0.05) are shown in red if they are up-regulated in the sensitization treated animals relative to control and in blue if they are down-regulated. Other genes are shown in black. The horizontal dotted line indicates the p_adj-value cut-off, while the vertical dotted line marks the point for zero fold change differences. One down-regulated gene without annotation is not show for hypothalamus (see Supplementary Table S2 for complete list).