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. 2021 Jul 30;100(30):e26772. doi: 10.1097/MD.0000000000026772

Table 2.

The incidence of IFD and breakthrough of IFD in patients who received posaconazole as a prophylaxis drug for 4 days or more.

Index Posaconazole as a prophylaxis drug continuously used for more than 4 days (N = 445) Breakthrough rate (%) 95% CI
IFD final diagnostic level
Probable IFD 7 1.6% 0.6%–3.2%
Possible IFD 27
Unclassified IFD 29
Non-IFD patients 382
IFD final diagnostic level of AML/MDS patients who received induction chemotherapy
Probable IFD 2 2.6% 0.3%–9.0%
Possible IFD 6
Unclassified IFD 7
Not IFD 63
IFD final diagnostic level of patients who received HSCT
Probable IFD 4 2.2% 0.6%–5.5%
Possible IFD 16
Unclassified IFD 11
Not IFD 153