Table 3.
Pairwise comparison results from network meta-analysis on kidney function progression.
| Canagliflozin | 0.83 (0.63–1.11) | 1.34 (1.08–1.66) | 0.85 (0.59–1.23) | 1.27 (0.92–1.75) | 1.38 (1.09–1.76) | 1.23 (0.96–1.57) | 1.32 (1–1.75) | 1.57 (1.3–1.91) | 1.12 (0.7–1.78) | 1.01 (0.69–1.47) |
| 1.2 (0.9–1.6) | Dapagliflozin | 1.6 (1.27–2.03) | 1.02 (0.7–1.49) | 1.53 (1.1–2.12) | 1.66 (1.28–2.15) | 1.47 (1.13–1.92) | 1.58 (1.18–2.13) | 1.89 (1.52–2.34) | 1.34 (0.83–2.16) | 1.21 (0.82–1.78) |
| 0.75 (0.6–0.93) | 0.62 (0.49–0.79) | Dulaglutide | 0.64 (0.46–0.88) | 0.95 (0.73–1.25) | 1.04 (0.87–1.23) | 0.92 (0.76–1.1) | 0.99 (0.79–1.24) | 1.18 (1.07–1.29) | 0.84 (0.54–1.29) | 0.75 (0.54–1.06) |
| 1.18 (0.81–1.7) | 0.98 (0.67–1.44) | 1.57 (1.13–2.18) | Empagliflozin | 1.5 (1–2.24) | 1.63 (1.15–2.3) | 1.44 (1.02–2.05) | 1.55 (1.07–2.26) | 1.85 (1.35–2.53) | 1.31 (0.78–2.24) | 1.19 (0.75–1.86) |
| 0.79 (0.57–1.08) | 0.65 (0.47–0.91) | 1.05 (0.8–1.37) | 0.67 (0.45–1) | Ertugliflozin | 1.09 (0.81–1.45) | 0.96 (0.72–1.3) | 1.04 (0.75–1.43) | 1.24 (0.96–1.59) | 0.88 (0.53–1.44) | 0.79 (0.52–1.19) |
| 0.72 (0.57–0.92) | 0.6 (0.47–0.78) | 0.97 (0.81–1.15) | 0.61 (0.43–0.87) | 0.92 (0.69–1.23) | Exenatide | 0.89 (0.72–1.09) | 0.95 (0.74–1.22) | 1.14 (0.99–1.31) | 0.81 (0.51–1.27) | 0.73 (0.51–1.04) |
| 0.82 (0.64–1.05) | 0.68 (0.52–0.89) | 1.09 (0.91–1.31) | 0.69 (0.49–0.98) | 1.04 (0.77–1.4) | 1.13 (0.91–1.4) | Liraglutide | 1.08 (0.83–1.39) | 1.28 (1.09–1.5) | 0.91 (0.58–1.43) | 0.82 (0.57–1.18) |
| 0.76 (0.57–1) | 0.63 (0.47–0.85) | 1.01 (0.81–1.26) | 0.64 (0.44–0.93) | 0.96 (0.7–1.33) | 1.05 (0.82–1.34) | 0.93 (0.72–1.2) | Lixisenatide | 1.19 (0.97–1.46) | 0.85 (0.53–1.36) | 0.76 (0.52–1.12) |
| 0.64 (0.52–0.77) | 0.53 (0.43–0.66) | 0.85 (0.77–0.93) | 0.54 (0.4–0.74) | 0.81 (0.63–1.04) | 0.88 (0.76–1.01) | 0.78 (0.67–0.91) | 0.84 (0.69–1.03) | Placebo | 0.71 (0.46–1.09) | 0.64 (0.46–0.89) |
| 0.89 (0.56–1.43) | 0.75 (0.46–1.21) | 1.2 (0.77–1.86) | 0.76 (0.45–1.29) | 1.14 (0.69–1.87) | 1.24 (0.79–1.95) | 1.1 (0.7–1.74) | 1.18 (0.74–1.9) | 1.41 (0.92–2.17) | Sotagliflozin | 0.9 (0.53–1.54) |
| 0.99 (0.68–1.45) | 0.83 (0.56–1.23) | 1.33 (0.94–1.86) | 0.84 (0.54–1.33) | 1.26 (0.84–1.91) | 1.37 (0.96–1.96) | 1.22 (0.85–1.75) | 1.31 (0.89–1.92) | 1.56 (1.13–2.16) | 1.11 (0.65–1.9) | Ssemaglutide |